Computational Biologist

Remote
Full Time
Experienced

Computercraft is seeking a biologist or bioinformatician with experience in the management and curation of functional classifications, with substantial expertise in scripting and design of data processing pipelines. The successful candidate will assist the Protein Domains team in evaluating external classification resources and model organism databases for their suitability as sources of novel protein (domain) family models, and in establishing respective data import strategies and pipelines. This work is aimed at improving coverage and accuracy of protein functional annotation as provided via conserved domain architecture, and at reducing the amount of manual curation work involved in the process. This is a full-time position which is currently remote.

Protein Domain resources are developed as a means to provide base-line protein functional annotation and support the consistent annotation of genome content. Responsibilities of the Bioinformatics Scientist will include data quality control and curation, import, annotation, and integration of external data, as well as communication with data providers and customers.

Our scientists work in a production-oriented, rather than research-oriented, environment supporting the National Center for Biotechnology Information (NCBI), part of the National Library of Medicine (NLM) at the National Institutes of Health (NIH). NCBI is one of the world’s premier biomedical center. It has one of the top 400 most visited websites worldwide, and its wide range of applications serve more users and more data than nearly any other U.S. Government agency. NCBI provides free access to petabytes of biomedical and genomic information, and scientists all over the world use its products.

Job Responsibilities

  • Critically evaluating datasets and functional annotations to assess quality
  • Evaluating software to aid in manual and automated construction of protein family models
  • Developing and monitoring automated dataflows for loading data to production databases
  • Providing critical expertise to NCBI in biological data curation of protein family models using subject matter knowledge and bioinformatics experience
  • User outreach to research scientists, data scientists, and clinicians
  • Interacting and collaborating with scientists within and outside the NIH

Desired Skills/Experience

  • Master’s degree
  • A strong publication record
  • A track record of outstanding research in functional characterization or classification of proteins, expert knowledge in genomics, systems biology, or proteomics
  • Research experience with model organisms (a plus)
  • Experience with comparative analysis of protein three-dimensional structure (a plus)
  • Expertise in bioinformatics of protein sequence analysis and tools including BLAST and multiple sequence aligners; expertise in constructing probabilistic models representing conserved families
  • Expertise in the development of robust workflows for automated data processing, including protein multiple sequence alignment and transfer of annotation in the context of functional ontologies
  • Proficiency in Python
  • Experience with SQL and shell scripting
  • Experience in interpreting complex biological problems, critically analyzing the scientific literature
  • Excellent communication and organization skills
  • A proven ability to successfully engage in multi-disciplinary collaborative research
  • Must be able to obtain a Public Trust and be located in the United States currently. We cannot accommodate remote work from any other International Location. 

The compensation for this position will be based on the experience of the successful candidate. The expected pay range for this position is $95,000 to $125,000 annually.

Computercraft offers a competitive salary, an excellent benefits package, the opportunity for a positive work–life balance with a standard 40-hour work week, and the chance to work alongside a team of highly accomplished professionals. Per Computercraft policies, all employees must be fully vaccinated against COVID-19.

EEO Employer—Disability/Veteran/Minority/Female/Sexual Orientation/Gender Identity

To learn about other Computercraft job opportunities, please visit the Careers section of our website: https://www.computercraft-usa.com/.

Share

Apply for this position

Required*
Apply with Indeed
We've received your resume. Click here to update it.
Attach resume or Paste resume
Attach resume as .pdf, .doc, .docx, .odt, .txt, or .rtf (limit 5MB) or Paste resume

Paste your resume here or Attach resume file

To comply with government Equal Employment Opportunity and/or Affirmative Action reporting regulations, we are requesting (but NOT requiring) that you enter this personal data. This information will not be used in connection with any employment decisions, and will be used solely as permitted by state and federal law. Your voluntary cooperation would be appreciated. Learn more.
Invitation for Job Applicants to Self-Identify as a U.S. Veteran
  • A “disabled veteran” is one of the following:
    • a veteran of the U.S. military, ground, naval or air service who is entitled to compensation (or who but for the receipt of military retired pay would be entitled to compensation) under laws administered by the Secretary of Veterans Affairs; or
    • a person who was discharged or released from active duty because of a service-connected disability.
  • A “recently separated veteran” means any veteran during the three-year period beginning on the date of such veteran's discharge or release from active duty in the U.S. military, ground, naval, or air service.
  • An “active duty wartime or campaign badge veteran” means a veteran who served on active duty in the U.S. military, ground, naval or air service during a war, or in a campaign or expedition for which a campaign badge has been authorized under the laws administered by the Department of Defense.
  • An “Armed forces service medal veteran” means a veteran who, while serving on active duty in the U.S. military, ground, naval or air service, participated in a United States military operation for which an Armed Forces service medal was awarded pursuant to Executive Order 12985.
Veteran status


Voluntary Self-Identification of Disability
Voluntary Self-Identification of Disability Form CC-305
OMB Control Number 1250-0005
Expires 5/31/2023
Why are you being asked to complete this form?

We are a federal contractor or subcontractor required by law to provide equal employment opportunity to qualified people with disabilities. We are also required to measure our progress toward having at least 7% of our workforce be individuals with disabilities. To do this, we must ask applicants and employees if they have a disability or have ever had a disability. Because a person may become disabled at any time, we ask all of our employees to update their information at least every five years.

Identifying yourself as an individual with a disability is voluntary, and we hope that you will choose to do so. Your answer will be maintained confidentially and not be seen by selecting officials or anyone else involved in making personnel decisions. Completing the form will not negatively impact you in any way, regardless of whether you have self-identified in the past. For more information about this form or the equal employment obligations of federal contractors under Section 503 of the Rehabilitation Act, visit the U.S. Department of Labor’s Office of Federal Contract Compliance Programs (OFCCP) website at www.dol.gov/ofccp.

How do you know if you have a disability?

You are considered to have a disability if you have a physical or mental impairment or medical condition that substantially limits a major life activity, or if you have a history or record of such an impairment or medical condition. Disabilities include, but are not limited to:

  • Autism
  • Autoimmune disorder, for example, lupus, fibromyalgia, rheumatoid arthritis, or HIV/AIDS
  • Blind or low vision
  • Cancer
  • Cardiovascular or heart disease
  • Celiac disease
  • Cerebral palsy
  • Deaf or hard of hearing
  • Depression or anxiety
  • Diabetes
  • Epilepsy
  • Gastrointestinal disorders, for example, Crohn's Disease, or irritable bowel syndrome
  • Intellectual disability
  • Missing limbs or partially missing limbs
  • Nervous system condition for example, migraine headaches, Parkinson's disease, or Multiple sclerosis (MS)
  • Psychiatric condition, for example, bipolar disorder, schizophrenia, PTSD, or major depression
Please check one of the boxes below:

PUBLIC BURDEN STATEMENT: According to the Paperwork Reduction Act of 1995 no persons are required to respond to a collection of information unless such collection displays a valid OMB control number. This survey should take about 5 minutes to complete.

You must enter your name and date
Human Check*